Chondroitin Sulfates Modulate Axon Guidance in EmbryonicXenopusBrain
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چکیده
منابع مشابه
Hyaluronic Acid Chondroitin Chondroitin Sulfates Dermatan Sulfate Keratosulfate Heparin
Polysaccharides (variously called as glycanes or polyholosides or polyosides) are high molecular weight carbohydrates which, on hydrolysis, yield mainly monosaccharides or products related to monosaccharides. They may also be regarded as polymeric anhydrides of simple sugars. D-glucose is the commonest component of polysaccharides. However, D-and L-galactose, D-mannose, D-xylose, L-arabinose as...
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It is essential to establish a library of glycosaminoglycan oligosaccharides from the chondroitin and dermatan sulfates to investigate their biological functions and structure-activity relationships (SARs). There are several approaches to obtain oligosaccharides using chemical and enzymatic degradation procedures; however, purification of each resulting oligosaccharide is complicated because of...
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The nervous system has the job of controlling and monitoring events throughout the whole body. But, unlike endocrine cells, which control their targets through long-range chemical cues, neurons communicate through direct cellular contacts, or synapses. As the information content of the electrical signals used by neurons is limited, much of the meaning in neural communication is conveyed by the ...
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Axon guidance by target-derived diffusible factors plays an important role in the development of the nervous system. This paper considers the constraints imposed on this process by the mathematics of diffusion. A point source continuously producing a factor into an infinite three-dimensional volume is considered as a model for both the in vivo and in vitro situation. Basic constraints for effec...
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Brain wiring is a highly intricate process in which trillions of neuronal connections are established. Its initial phase is particularly crucial in establishing the general framework of neuronal circuits. During this early step, differentiating neurons extend axons, which reach their target by navigating through a complex environment with extreme precision. Research in the past 20 years has unr...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 1998
ISSN: 0012-1606
DOI: 10.1006/dbio.1998.9006